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PRL-8-53 Neurofluid

14,50 €

  •   improves working and long-term memory
  •   has anti-depressant effects
  •  has diastolic effects

More details

Availability: This product is no longer in stock

PRL-8-53 (by. IUPAC-3- [2- [benzyl (methyl) amino] ethyl] benzoate) is a synthetic derivative of benzoic acid and phenethylamine. It was shown that it combats catatonia and ptosis caused by reserpine – a naturally occuring alkaloid that flushes out catecholamines from the central nervous system. Nonetheless, the exact mechanism of this substance is unknown. Study results suggest a positive effect of PRL-8-53 on the activity of the cholinergic and dopaminergic systems, and an inhibiting effect on the activity of the serotonin system.2

Studies with healthy individuals have shown that PRL-8-53 slightly improved the functioning of the working memory, and significantly improved long-term memory, especially in older participants of the study.2,3

Additionally, this compound has a positive effect on mood and an anti-depressant effect.1 Studies on animals have also determined the diastolic effects of PRL-8-53; wherein the spasmolitic activity of PRL-3-53 was three times as much as the activity of papaverine, which is a derivative of drotaverine (No-Spa) - a substance widely used in cases of spastic smooth muscles.1,2

Dosage

Clinical trials on healthy participants used doses of 5 mg.2
As suggested in patent application, a daily dose is 0.01-4 mg/kg, where the most preverable dose range is 0.05-1.2 mg/kg.1

Synergy

Lack of data.

Interaction

Lack of data.

Side effects

There were no reported side effects in humans, however, studies in rats have shown that at a dose of 160 mg/kg (13-26 mg/kg in higher mammals, including humans) reduces the motor activity by 50%.2

Bibliography

1. Hansl, N. R. Process for hydrolyzing 3-trifluoromethyl phenethylamines. 1–12 (1974).
2. Hansl, N. R. & Mead, B. T. PRL-8-53: enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent. Psychopharmacol. (Berl). 56, 249–253 (1978).
3. Hansl, N. R. A novel spasmolytic and CNS active agent: 3-(2-benzylmethylamino ethyl) benzoic acid methyl ester hydrochloride. Experientia. 30, 271–2. (1974).

Grade 
08/17/2017

Kompletnie na mnie nie działa.

Dawkowane przez tydzień pod język, nie przyniosło absolutnie żadnych rezultatów.

  • 1 out of 2 people found this review useful.
Grade 
06/17/2017

Najlepszy wzmacniacz pamięci!

Dla mnie nie ma lepszego produktu jeśli chodzi o typowy nootrop na konsolidację pamięci, efekty widoczne po tygodniu stosowania. Uczyłem się nowej biblioteki w języku programowania Ruby, efekty zapamiętywania podczas kodzenia projektu nad wyraz widoczne.
Brawo Allchemy.

  • 1 out of 1 people found this review useful.
Grade 
10/26/2016

dobre, ale do sporadycznego brania

produkt wprowadza mnie na wyższy poziom intelektualny, zaczynam rozumieć rzeczy, które wcześniej nie były dla mnie dostępne. Ma to jednak swoją cenę. Obniża poziom serotoniny co jest odczuwalne przy wyższych dawkach lub przy braniu tego w trybie ciągłym. Dla sporadycznego brania ( jak trzeba się czegoś nauczyć jest niezłe)

  • 3 out of 4 people found this review useful.
Grade 
06/09/2016

CZW., 9 CZE 2016

Kiedy produkt będzie dostępny?

  • 2 out of 5 people found this review useful.

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PRL-8-53  Neurofluid

PRL-8-53 Neurofluid

  •   improves working and long-term memory
  •   has anti-depressant effects
  •  has diastolic effects

Write a review

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RELIABLE INFORMATION

Our website contains objective and reliable information based on current scientific publications. We care about maintaining a high level of quality standards in the articles we publish by keeping our site up-to-date and making sure the information we place on it is clear and transparent. The authors of the website content are scientists from UJ, a neuropsychologist and a chemist.


PRACTICAL EXPERIENCE

At Allchemy.eu, professionalism is of our utmost interest. Our team consists of a neuropsychologist, a pharmacist, a chemist, a psychologist, and a physicist. We don't just “do business.” This is our passion and we test all available chemical agents on ourselves, selecting the most interesting ones while discarding those that we deem dangerous or harmful.


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We care about your satisfaction. That is why you can always return an originally sealed product within 30 days of purchase, no reason necessary.

LABORATORY QUALITY TESTING

The products found in our catalog come from tested and trusted sources, are certified, and undergo laboratory analyses- i.e HPLC, GC, TLC; 1 H NMR spectroscopy, IR, AAS, and the physiochemical parameters -temperature melting point, pH, humidity.


VACCUUM PACKAGING

Vaccuum packaging protects our chemical agents from the effects of oxygen and air moisture. Oxygen is a very reactive compound that causes the oxidation and breakdown of certain compounds, while water facilitates the development of bacteria and processes of hydrolysis. Thanks to the vaccuum packaging of sensitive compounds, our clients receive top quality products that can also be kept for later use. Nevertheless, it is important to remember to tightly reseal the packaging by removing any air from the bag and precisely closing the seal. This will pay off!