We use cookies to make the website faster and easier. Do you want to know what information we hold? See the Privacy Policy.

close
Curcumin View larger

Curcumin

4,95 €

  •   has anti-inflammatory and anti-oxidative properties
  •  improves the functioning of the brain and reducing its risk of disease
  •  slows the aging process and protects against diseases of old age

More details

Availability: In stock!

Curcumin is a natural polyphenol obtained from the rhizomes of Curcuma longa. Curcuma has been used for a few thousand years in Ayurvedic and Chinese traditions for culinary purposes as well as religious and medical. Curcumin is the main ingredient of turmeric- the orange spice widely used in Eastern cuisine. Labeled as E100, it is used as a food coloring. Studies and clinical trials on Curcumin have shown that this compound is characterized by a very broad spectrum of effects and can be an excellent therapeutic or preventive diet supplement.

Mechanism of action

Curcumin reduces the level of inflammatory cytokines and because of the stable structure of the molecule, it is a powerful antioxidant and effective scavenger of free oxygen radicals, which together with a chronic inflammatory condition are considered to be a key factor in the development of various diseases- such as diabetes, arthritis, neurodegenerative diseases, cardiovascular disease or cancer. Additionally, by activating gene expression response to oxidative stress, this compound stimulates the inner workings of the body's defenses enhancing the protective effect.1

Thanks to these attributes, this substance proves useful in cancer prevention as well as a cancer treatment aid, especially in the lungs and digestive tract. It was proven that it inhibits metastases and can even kill cancer cells through induction of apoptosis.2,3 Studies have demonstrated that, thanks to its anti-inflammatory effects, curcumin protects dopaminergic neurons and its inhibitory effect on the formation of amyloid plaques further enhances its therapeutic potential in the treatment of Parkinson's disease and Alzheimer's.4,5

Regeneration and neurogenesis

Curcumin induces neurogenesis, which is the creation of nerve cells in the brain. Chronic stress causes a decrease in the intensity of this process in the hippocampus- the key structure responsible for creating new memory traces, which tends to be the cause of depression disorders and the weakening of various cognitivie functions. Studies have shown that curcumin restores the normal level of neurogenic activity just as effectively as the commonly used SSRI anti-depresssant drugs.6,5 Moreover, it was shown that curcmin counteracts the negative effects of stroke and traumatic brain injury to synaptic plasticity.7

Dosage

Curcmin has practically zero solubility in water, and thus, is barely absorbed in the gastrointestinal tract. Because of this, it can be consumed in amounts up to 12 grams. This compound is soluble in oil and alcohol and piperine contained in pepper can greatly potentiate the level of absobrtion of curcumin from the gastrointestinal tract.2 In combination with piperine or pepper, the recommended dose is 80-500 mg.9 A microspoon facilitating dosage measurement is included!

Interesting facts

Curcumin is sometimes also used as poultices for insect bites and leeches, wounds and skin inflammation.8

Synergy

Resveratrol9, many different anti-cancer meds9, pepper (piperine).2

Interaction

Curcumin may interact with such drugs as aspirin, non-steroidal anti-inflammatory drugs, diabetes medications, statins, anticoagulants and drugs for hypertension. It can also interact with other supplements that lower blood clotting- such as ginkgo, ginseng and garlic.

Side effects

Curcumin is considered safe. Some people may experience indigestion, nausea, dizziness or diarrhea.8 Particular caution is advised for people with blood coagulation disorders, diabetes and iron deficiency. Not recommended to take curcumin by people suffering from gallstones.8

 

Bibliography

1. Hu, S. et al. Clinical development of curcumin in neurodegenerative disease. Expert Rev. Neurother. 15, 629–637 (2015).
2. Ghosh, S., Banerjee, S. & Sil, P. C. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update. Food and Chemical Toxicology (Elsevier Ltd, 2015). doi:10.1016/j.fct.2015.05.022
3. Hsu, C. H. & Cheng, A. L. in The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease 595, 471–480 (2007).
4. Fu, W., Zhuang, W., Zhou, S. & Wang, X. Plant-derived neuroprotective agents in Parkinson’s disease. Am J Trans 7, 1189–1202 (2015).
5. Xu, Y. et al. Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats. Brain Res. 1162, 9–18 (2007).
6. Kim, S. J. et al. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J. Biol. Chem. 283, 14497–14505 (2008).
7. Wu, A., Ying, Z. & Gomez-Pinilla, F. Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition. Exp. Neurol. 197, 309–317 (2006).
8. WebMD. Turmeric.
9. Du, Q. et al. Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells. Oncol. Rep. 29, 1851–1858 (2013).

DISCLAIMER
Allchemy.eu is a distributor of chemicals of the highest quality intended solely for research. The information provided in the description has not been confirmed by GIF, GIS, or EFSA and should not be used to treat, diagnose, or prevent any disease.  Our sevice is inteded for adults only and we are not responsible for the inappropriate use of our products.  

No customer comments for the moment.

Write a review

Curcumin

Curcumin

  •   has anti-inflammatory and anti-oxidative properties
  •  improves the functioning of the brain and reducing its risk of disease
  •  slows the aging process and protects against diseases of old age

Write a review

Ask a question

NO registration required!

If the question you have has not yet been answered here, use the form below to ask something about this addon.

(optional)
*(Required to be notified when an answer is available)

RELIABLE INFORMATION

Our website contains objective and reliable information based on current scientific publications. We care about maintaining a high level of quality standards in the articles we publish by keeping our site up-to-date and making sure the information we place on it is clear and transparent. The authors of the website content are scientists from UJ, a neuropsychologist and a chemist.


PRACTICAL EXPERIENCE

At Allchemy.eu, professionalism is of our utmost interest. Our team consists of a neuropsychologist, a pharmacist, a chemist, a psychologist, and a physicist. We don't just “do business.” This is our passion and we test all available chemical agents on ourselves, selecting the most interesting ones while discarding those that we deem dangerous or harmful.


INSTANT SHIPPING

Do you value time and comfort? We ship our packages through DPD courier, Polish Post Office, and Inpost post boxes- every day! Orders made before 10 AM are shipped on the same day!


HASSLE-FREE RETURNS

We care about your satisfaction. That is why you can always return an originally sealed product within 30 days of purchase, no reason necessary.